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Caltech biologists show that microRNA-146a protects stem cells during inflammation

from The Medical News

When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer. Now, a team of researchers led by biologists at the California Institute of Technology has found that, in mouse models, the molecule microRNA-146a acts as a critical regulator and protector of blood-forming stem cells during chronic inflammation. more


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