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Clock is ticking: New acetaminophen combo limitations coming soon

from By Jason Poquette

Beginning in January, manufacturers of combination prescription products containing acetaminophen are expected to limit their APAP content to no more than 325 mg per dose. The significance of this is that many narcotic combination products currently being dispensed will soon no longer be compliant with these guidelines. The most significant impact for this group would be the changes related to hydrocodone/acetaminophen combination products, many of which still contain 500 mg of APAP or more. more


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