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Unprecedented, atom-scale simulation of G protein-coupled receptor site's transformation

from News-medical.net

Roughly 40 percent of all medications act on cells' G protein-coupled receptors. One of these receptors, beta 2 adrenergic receptor site, naturally transforms between two base configurations; knowing the precise location of each of approximately 4,000 atoms is crucial for ensuring a snug fit between it and the drug. more


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