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Depression-causing protein identified

from U-T San Diego

A potential new target for antidepressant therapy has been reported in a study published recently in Nature Medicine. Elevated levels of a protein called REDD1 cause neuronal atrophy and anxiety and depressive behaviors in rats, according to the study. People with major depressive disorder also have elevated levels of this protein in the prefrontal cortex, as determined by postmortem examination, the researchers found. more


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