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Understanding the role of sterility testing in compounding

from Pharmacy Purchasing & Products

First appearing in the British Pharmacopoeia in 1932, the sterility test included the basic features of the test we use today: Two media, a prescribed dilution scheme, and a defined incubation time. Shortly thereafter, the USP also adopted a sterility test; the first version, which appeared in 1935, included one medium, a dilution scheme and a retest provision to evaluate failures. Perhaps surprisingly, today's sterility test has changed little from its initial origins. more

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