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Risk of antibody-mediated rejection in kidney transplant recipients with anti-HLA-C donor-specific antibodies

from American Journal of Transplantation (login required)

Anti-HLA donor-specific antibodies cause acute and chronic antibody-mediated rejection. However, the clinical relevance of anti-HLA-C antibodies remains unclear. We evaluated the clinical relevance of the presence of anti-HLA-C DSA at day 0 in renal transplant recipients. In this retrospective, case-controlled study, 608 patients who underwent kidney transplantation between August 2008 and March 2012 were screened for the presence of isolated anti-HLA-C DSA at day 0. more


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