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A new model of liver regeneration

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Harvard Stem Cell Institute scientists at Boston Children's Hospital have new evidence in mice that it may be possible to repair a chronically diseased liver by forcing mature liver cells to revert back to a stem cell-like state. The researchers, led by Fernando Camargo, Ph.D., happened upon this discovery while investigating whether a biochemical cascade called hippo, which controls how big the liver grows, also affects cell fate. more

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