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Naloxegol shows efficacy against symptoms of opioid-induced constipation

from Pain Medicine News

Naloxegol, an oral, peripherally acting μ-opioid receptor antagonist, appears safe and effective in relieving opioid-induced constipation. OIC occurs in 40 to 60percent of individuals taking opioids, and is a unique form of constipation, said Dr. William D. Chey, who presented the findings of two identical, randomized controlled, phase III trials of naloxegol at a recent meeting. more


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