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Heparin in stent patients: New love for an old friend

from MedPage Today

Among patients with ST-elevation myocardial infarction undergoing percutaneous coronary intervention (PCI), bivalirudin (Angiomax)-based anticoagulation may increase the relative risk of acute stent thrombosis or recurrent MI when compared with similar patients treated with heparin. The trade-off, according to Matthew A. Cavender, M.D., and Marc S. Sabatine, M.D., of the TIMI Study Group at Brigham and Women's Hospital in Boston — analyzing data from 16 trials involving almost 34,000 PCI patients — is an apparent decrease in bleeding with bivalirudin. more

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