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The role of biofilms in chronic infections

from Clinical Advisor

What are some of the most challenging clinical problems you see in everyday practice? Do they include chronic sinusitis refractory to multiple antibiotics? Recurrent, difficult-to-treat urinary tract infections? Poorly healing ulcers resistant to topical antibiotics and successive debridement? Seemingly ineradicable bacterial vaginosis and Candida vaginitis? Or, alternatively, chronic progressive periodontal disease with not just local dental but also systemic manifestations, such as heightened risk for cardiovascular disease? When antibiotics fail, we put the blame on bacterial resistance. more

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