Genes tied to immune response differentially expressed in kids with Crohn's, UC
The expression of genes related to mucosal immune responses differs between ulcerative colitis (UC) and colon-only Crohn's disease (CD) in pediatric patients, researchers report. "At diagnosis, there are specific differences in mucosal cytokine response between children with ulcerative colitis and Crohn's colitis that may be useful for distinguishing these diseases and for predicting response to therapy," Dr. Michael J. Rosen from Cincinnati Children's Hospital Medical Center, in Ohio, told Reuters Health by email.
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