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CF guidelines: Greater reliance on mutation classifications

from Medscape (free login required)

New consensus guidelines for the diagnosis of cystic fibrosis (CF) further standardize the diagnostic criteria for infants through adults and may inform targeted treatment based on specific genetic variants of the pulmonary disease. Of particular note, the consensus recommendations, developed for the Cystic Fibrosis Foundation by an international panel of experts and published online in the Journal of Pediatrics, recommend that clinicians use the most recent classifications for CF transmembrane conductance regulator mutations to diagnose the disease in patients of all ages. more


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