Increased self-harm, depression risks associated with 5-alpha-reductase inhibitors
While 5-alpha-reductase inhibitor use did not increase the risk of suicide in older men, it did increase the risk of self-harm and depression compared with men who were unexposed to the treatment, according to findings published in JAMA Internal Medicine. "Benign prostatic hyperplasia (BPH) is a major contributor to lower urinary tract symptoms (LUTS) in older men," Blayne Welk, MD, MSc, from the Department of Surgery at Western University in Ontario, Canada, and colleagues wrote.
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