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New biomarker signals poor response in prostate cancer

from Medscape (free login required)

A new test can identify men with castration-resistant prostate cancer (CRPC) who are likely to have a poorer response to the targeted hormonal therapies abiraterone acetate (Zytiga, Janssen) and enzalutamide (Xtandi, Medivation/Astellas), say British researchers. Many prostate cancers rely on the androgen receptor gene (AR) to grow, the authors explain. The new test finds tumors with multiple copies of AR. more

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