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Scientists identify RIOK1 enzyme as new target for cancer therapy

from News-Medical

Researchers have discovered that the enzyme RIOK1 collaborates with the RAS protein, which is often mutated in tumors and therefore promotes tumor growth and the development of metastases. These secondary tumors are spread by the primary tumor, if it is not removed in time, and are the cause of death in most cancer patients. The researchers believe it may be possible to use so-called inhibitors to block the enzymatic activity of RIOK1, thereby slowing down the disease's progression. The team has recently published its findings in the translational journal EBioMedicine. more


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