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Study explores periodontal status of patients with Chédiak-Higashi syndrome

from American Association for Dental Research

The International and American Associations for Dental Research have published an article "Periodontitis in Chédiak-Higashi Syndrome: An Altered Immunoinflammatory Response" in the JDR Clinical & Translational Research. In this study, Vivek Thumbigere Math, from the National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institutes of Health (NIH), and authors from other institutes of NIH as well as the State University of Campinas, Piracicaba Dental School, Piracicaba, SP, Brazil sought to determine the periodontal status of patients with severe and mild forms of Chédiak-Higashi syndrome, a rare genetic disorder caused by mutations in the lysosomal trafficking regulator gene — a gene that codes for a protein that helps with protein packaging and transport within cells. more

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