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Hypofractionated nodal radiation therapy for breast cancer was not associated with increased patient-reported arm or brachial plexopathy symptoms

from International Journal of Radiation Oncology

Two cancer registries were used to identify subjects who received CT-planned, nodal RT for pT1-3, pN0-2, M0 breast cancer from 2007-2010 at two cancer institutions. Following ethics approval, patients were mailed an explanatory letter and the Self-reported Arm Symptom Scale (SASS), a validated instrument with 8 questions about arm symptoms and 5 related to activities of daily living (ADL). Clinico-pathologic characteristics and SASS scores were compared between HF/CF cohorts using non-parametric analysis, chi-squared analysis and multivariate ordinal regression. more


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