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Hydromorphone vs prochlorperazine/diphenhydramine for acute migraine pain relief

from Clinical Pain Advisor

Intravenous (IV) treatment with hydromorphone was found to provide less pain relief for acute migraine than IV prochlorperazine in patients admitted to the emergency department, according to a study published in Neurology. Investigators evaluated pain relief outcomes in 127 patients with acute migraine admitted to 2 emergency departments in New York City. All parties involved — including investigators, patients, clinicians, and research personnel — were blinded during the treatment phase of this study. more


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