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Intranasal ketamine or fentanyl for children: Similar analgesia, disproportionate side effects

from Anesthesiology News

Intranasal ketamine causes more minor side effects, such as dizziness, than intranasal fentanyl used as analgesia for children with assumed single-extremity fractures, according to researchers. The double-blind, randomized controlled trial in 82 children found that while pain relief was similar at 20 minutes between the two groups, the cumulative number of side effects in the ketamine group was 2.2 times higher than in the fentanyl group. more

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