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Sudden cardiac arrest, ventricular arrhythmia risk examined with sulfonylureas

from Monthly Prescribing Reference

Glyburide may be associated with a reduced risk of sudden cardiac arrest and ventricular arrhythmia (SCA/VA) when compared with glipizide. Findings from this retrospective cohort study were published in the journal Diabetes Care. Using U.S. Medicaid claims (1999–2010) from five states, the researchers sought to examine the association between individual sulfonylureas (glyburide, glimepiride, glipizide) and outpatient-originating SCA/VA; glipizide was considered the reference exposure. more

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