Using propofol for difficult-to-treat headaches in the ED
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Emergency physicians are not only tasked with determining which headaches may be the most life-threatening, but also with figuring out the most effective ways to treat them. The standard headache cocktail — a neuroleptic agent, ketorolac, diphenhydramine, and dexamethasone — is ingrained as the most effective first-line approach for alleviating migraine and tension headaches in the majority of patients. We often use this approach in the ED, and although it is certainly effective, another novel strategy that deserves discussion is propofol.
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