Cells that bridge bone and teeth are a novel tool to study complex bone diseases
from Science Trends
Those of us that have worn braces during childhood have probably never realized that this force on teeth evokes unique cellular responses of the cells that are located in the tiny gap of approximately 0.1 millimeter between the tooth and the bone socket into which the tooth is embedded. Teeth migrate through bone by induction of bone break-down at the “pull”-side and by inducing bone formation at the “push”-side. The space between tooth and bone is the periodontal ligament, and, similar to muscle-to-bone ligaments that are more commonly known, fibroblasts from this ligament secure tight anchoring of teeth into bone.
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