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Graft dysfunction in simultaneous pancreas kidney transplantation (spk): Results of concurrent kidney and pancreas allograft biopsies

from American Journal of Transplantation

Simultaneous pancreas and kidney transplants offer significant therapeutic advantages but present a diagnostic approach dilemma in the diagnosis of rejection. Since both organs are from the same donor the kidney has been traditionally treated as the “sentinel” organ to biopsy, presumably representing the status of both allografts. Truly concurrent biopsy studies, however are needed to confirm this hypothesis. We examined 101 concurrent biopsies from 70 patients with dysfunction in either or both organs. more

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