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Trial by fire: Critics demand that a huge sepsis study be stopped

from The New York Times via WRAL-TV

A large government trial comparing treatments for a life-threatening condition called sepsis is putting participants at risk of organ failure and even death, critics charge, and should be immediately shut down. A detailed analysis of the trial design prepared by senior investigators at the National Institutes of Health Clinical Center in Bethesda, Maryland, concluded that the study "places seriously ill patients at risk without the possibility of gaining information that can provide benefits either to the subjects or to future patients." In interviews, the scientists leading the study defended its design, saying that participants are receiving all the care that sepsis patients normally would receive. more

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