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Making old antibiotics new again

from University of Colorado Boulder via Infection Control Today

With antibiotic-resistant “superbugs” now infecting 2 million people per year and a dearth of new medications in the pipeline to treat them, University of Colorado Boulder researchers are taking a novel approach to addressing the looming public health crisis: They’re helping develop new drugs to make old drugs work better. “We believe the compounds we’ve discovered have the potential to rejuvenate existing antibiotics — to make bacteria that are now insensitive to multiple drugs sensitive again,” said Corrie Detweiler, a professor of molecular, cellular and developmental biology who recently outlined her discovery in the journal PLOS Pathogens. more

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