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Using Water and Gold, Australian Researchers Discover 'Universal Cancer Biomarker'

from FierceBiotech

Australian researchers at the University of Queensland have discovered a unique DNA structure that appears to be shared by many cancers and could be used to develop a simple diagnostic test that could be performed in under 10 minutes with the naked eye. When circulating tumor DNA fragments are placed in water, they begin to fold into 3-D shapes different than DNA from healthy cells — driven by the dense clusters of methyl groups found along DNA molecules that have been reprogrammed by cancer.

Those specific structures can then be separated from the solution by sticking them to bare metal surfaces such as gold, the researchers found. more


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