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Study refutes effectiveness of drug combination for treatment-resistant depression

from By Dorothy L. Tengler

Many treatment options are available for depression, but how well treatment works depends on the type of depression and its severity. Antidepressants take time — usually 2 to 4 weeks — to work, and often, symptoms such as sleep, appetite and concentration problems improve before mood lifts. However, despite advances in understanding the psychopharmacology and biomarkers of major depression and the introduction of several novel classes of antidepressants, only 60 to 70 percent of patients with depression respond to antidepressant therapy. more

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