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Sudden symptomatic improvement predicts response to antidepressant therapy

from Psychiatry Advisor

Sudden responses to antidepressants occur in approximately one-third of patients and can result in stable gains, even in a geriatric population, according to an article published in the Journal of Clinical Psychiatry. True response to antidepressant therapy has long been held to occur incrementally, during a period of several weeks or more, and sudden responses that occur early during the course of a clinical trial are thought to be transient and characteristic of a placebo response. Yet despite the persistence of this idea, there is little evidence to support it. more


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