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Scutellarin Suppresses Proliferation And Promotes Apoptosis in A549 Lung Adenocarcinoma Cells Via AKT/mTOR/4EBP1 and STAT3 Pathways

from Thoracic Cancer

BACKGROUND: Scutellarin (SCU), a flavonoid isolated from Erigeron breviscapus (Vant.) Hand.-Mazz., increases autophagy and apoptosis in the adenocarcinoma A549 cell line, which is resistant to cisplatin. However, whether SCU alone has antitumor activity against non-small cell lung cancer (NSCLC) is unknown. more


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