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Impact of hemoglobin breakdown products in the spectral analysis of burn wounds using spatial frequency domain spectroscopy

from Journal of Biomedical Optics

Burn wounds and wound healing invoke several biological processes that may complicate the interpretation of spectral imaging data. Through analysis of spatial frequency domain spectroscopy data (450 to 1000 nm) obtained from longitudinal investigations using a graded porcine burn wound healing model, we have identified features in the absorption spectrum that appear to suggest the presence of hemoglobin breakdown products, e.g., methemoglobin. more

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