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Contemporary treatments in prostate cancer focal therapy

from UroToday

Radical treatments for prostate cancer are associated with significant morbidity, including incontinence and erectile dysfunction. Advances in the field of prostate MRI and desire to reduce treatment morbidities have led to a rapid growth in focal treatments for prostate cancer. Here, we review novel focal prostate cancer treatments and their associated recent clinical data, with a particular focus on data reported within the last 24 months. High-intensity focal ultrasound, focal laser ablation, irreversible electroporation, focal cryotherapy and photodynamic therapy have been used as treatment modalities for localized prostate cancer treatment. Despite the great variety of treatment techniques, each of these modalities is characterized by a significant rate of prostate cancer persistence within treatment zones (6-50 percent) and the presence of residual cancer within the prostate on rebiopsy (24-49 percent). more

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