Immune system is potential culprit in causing cavities, damaging fillings
from Acta Biomaterialia via Medical Xpress
A new study by researchers at the University of Toronto's Faculty of Dentistry provides the first evidence that the body's own defence system could be a major contributor to tooth decay and filling failure. The study shows that the decay of dentin and fillings is caused not just by bacteria alone — as has been the model understood by science for decades — but through the unique activity of oral immune cells known as neutrophils, which potentially enhance the effects of bacteria. "No one would believe that our immune system would play a part in creating cavities," says Associate Professor Yoav Finer, the lead author of the study and the George Zarb/Nobel Biocare chair in prosthodontics at the Faculty of Dentistry. "Now we have evidence."
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