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A population-based cohort study: Risk of severe maternal morbidity or death in relation to elevated hemoglobin A1c preconception, and in early pregnancy

from PLOS Medicine

The prevalence of diabetes mellitus (DM) and obesity have rapidly increased worldwide. Serum glycated hemoglobin A1c (A1c), expressed as an absolute percent (e.g., 5.5%), offers a convenient and representative measure of average blood glucose control among individuals with DM and of prediabetes in obese adults. Prepregnancy DM and maternal obesity are each associated with a higher risk of congenital anomalies and preterm birth. more

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