How does ketamine work as an antidepressant? It's complicated
The anesthetic ketamine shows promise as a rapid treatment for difficult-to-treat depression, but scientists don't know exactly how it works. Now, a small study hints that, among other effects, ketamine may activate a specific receptor in the brain that interacts with serotonin, a brain chemical implicated in many mood disorders. One caveat: The study included just 30 individuals.
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