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Details about broadly neutralizing antibodies provide insights for universal flu vaccine

from University of Chicago Medical Center via Medical Xpress

New research from an immunology team at the University of Chicago may shed light on the challenges of developing a universal flu vaccine that would provide long-lasting and broad protection against influenza viruses. The study, published recently in Immunity, explores the behavior of polyreactive antibodies — antibodies that are capable of binding to more than one distinct antigen — in an effort to understand their role against influenza viruses. The researchers identified that broadly neutralizing antibodies are commonly polyreactive and are preferentially induced by novel and pandemic-level influenza viruses. more

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