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AAGP
Attention Training Directors and Trainees! Spread the word about the GMHF Scholars Program. Benefits include a one year membership, comp registration for annual meeting, travel stipend, full day of scholars' sessions and networking at the annual meeting, and participation in an academic project. For more information, go to www.aagponline.org/scholars. Applications due October 1.
Want to help support a GMHF Scholar at the 2016 Annual Meeting? Click here to donate!
Pharmacy Times
Because current healthcare practice focuses on diagnosing and prescribing, the need to taper, reduce, or discontinue inappropriate medication therapy receives relatively little attention. Few clinical guidelines cover drug deprescribing, and this lack of evidence-based direction contributes to prescribers' hesitancy or reluctance to touch treatment regimens that may have originated from a different practice setting.
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Medical News Today
A new study indicates that a drug may represent a novel therapeutic target for Alzheimer's disease after researchers used it to treat the disease in rats. At present, the U.S. Food and Drug Administration (FDA) have approved five medications to treat Alzheimer's disease. However, while these only mask the symptoms of Alzheimer's, the researchers were able to treat the disease itself in rats using a chemical called IRL-1620.
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Medscape
Late-life depression can be difficult to treat, and in elderly patients, response to antidepressant therapy can vary considerably, new research suggests.
In a study that looked at longitudinal patterns of changes in depressive symptoms in older adults prescribed the antidepressant venlafaxine XR (Effexor XR, Wyeth Pharmaceuticals Inc), severe baseline depression tended to predict lack of response after 12 weeks of treatment.
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By Denise A. Valenti
 Using a large meta-analysis study of the literature related to Alzheimer's disease, scientists identified four medical treatments and four dietary habits that may contribute to a lower risk of Alzheimer's. The research was reported in a recent issue of Journal of Neurology, Neurosurgery and Psychiatry. The scientists found medical treatment with estrogen, statins, anti-hypertensive medications or nonsteroidal anti-inflammatory drugs were protective factors related to Alzheimer's disease.
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HealthDay via Psychiatry Advsior
Neither exercise nor supplements such as omega-3 fatty acids seem to preserve cognitive function in the elderly, according to research published in the Journal of the American Medical Association. Kaycee Sink, M.D., medical director of the Kulynych Memory Assessment Clinic at the Wake Forest School of Medicine, and colleagues found no significant difference in mild cognitive impairment or dementia among individuals aged 70 and 89 who participated in physical activity and those who were assigned to health education workshops and arm stretching.
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Medscape
In a randomized trial of community-dwelling seniors over age 75 with hypertension and only mild cognitive deficits, stopping antihypertensive therapy for 16 weeks did not improve their short-term cognitive, psychological, or general function. These findings from the Antihypertensive Treatment in Elderly People (DANTE-Leiden) were published online August 24, 2015 in JAMA Internal Medicine. This trial is the first to assess the narrowly defined research question of the effect of discontinuing antihypertensive treatment on cognitive function in older persons, the authors write. "Therefore, we can only conclude that discontinuation of antihypertensive treatment in older persons with mild cognitive deficits and without serious cardiovascular disease has no short-term cognitive benefit."
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The Independent
Scientists have developed a blood test to estimate how quickly someone is ageing. They believe it could be used to predict a person’s risk of developing Alzheimer's disease as well as the "youthfulness" of donated organs for transplant operations. The test measures the vitality of certain genes which the researchers believe is an accurate indication of a person’s "biological age," which may be younger or older than their actual chronological age.
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