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| HEALTH CARE NEWS AND UPDATES |
The Washington Post
The Food and Drug Administration recently cleared the first treatment for patients with advanced breast cancer caused by BRCA mutations, which are genetic defects that raise the risk of malignancies.
The drug, called Lynparza, already is approved for certain patients with advanced ovarian cancer associated with the same mutations. Richard Pazdur, director of the FDA's Oncology Center of Excellence, said in a statement that expanding the approval to breast-cancer patients "demonstrates the current paradigm of developing drugs that target the underlying genetic causes of a cancer, often across cancer types."
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Cure
Ever wonder how far back cancer diagnoses actually go? Well, according to an international group of researchers, the oldest known cases of multiple myeloma and breast cancer date back to two Egyptian mummies.
A team of researchers, including members from the University of Granada’s anthropology group in Spain, conducted CT scans of two mummies found in the pharaonic necropolis of Qubbet el-Hawa in Aswan, Egypt.
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MedPage Today
A greater abundance of certain bacteria in the oral microbiome were associated with a decreased risk of head and neck squamous cell cancer (HNSCC) in several patient cohorts, according to investigators.
Specifically, Richard B. Hayes, DDS, PhD, NYU Langone Health, New York University School of Medicine, and colleagues found the association between a decreased risk of HNSCC and a greater abundance of genera Corynebacterium and Kingella. As noted by Hayes and his colleagues, there are more than a half million new cases of cancer of the oral cavity, pharynx, and larynx diagnosed annually worldwide, as well as 380,000 deaths related to the disease.
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Enjoy our journals? There’s an app for those! Journals such as those from the American Cancer Society ™, Journal of Surgical Oncology, Cancer Science and more are now available for your iPad and iPhone. Sample issues and abstracts, as well as open articles, can be accessed for free. A subscription to the journal is required to read the full text. Click here to learn more!
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Cure
Desmoplastic melanoma is an unmet need in the oncology field, especially since conventional understanding of the disease assumed that immunotherapy agents would not work because the tumor tissue is so dense.
But new research is finding that anti-PD-1/PD-L1 inhibitors can, in fact, play a role in the treatment of desmoplastic melanoma, which makes up about 4 percent of all melanoma cases.
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Journal of Clinical Pathways
A recent study identified substantial barriers to standard-of-care therapy for limited-stage small cell lung cancer (SCLC), including government insurance coverage.
Results of the study were published in JAMA Oncology.
Combined-modality therapy for limited-stage SCLC (chemotherapy and radiation therapy) is considered standard of care as an upfront treatment strategy. However, there may be barriers to utilization in the United States, and further research is necessary to better define these potential barriers.
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Novodiax is soon bringing to market 10-minute fast, sensitive and simple Immunoassay (IHC) kits for in vitro diagnostic use to address unmet needs in the intraoperative surgical oncology sector. Learn More
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AJMC
Lung cancer is the most common cause of cancer death in the United States, with over 158,000 people dying from the disease each year. While the standard-of-care therapy for patients with stage III non–small-cell lung cancer (NSCLC) is chemotherapy and radiotherapy (CRT), there are treatment disparities among octogenarians and nonagenarians, according to a study published in CANCER.
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The Lead via Medical Xpress
Women who have undergone hormonal therapy for breast cancer are at increased risk of developing chronic conditions later in life, according to new research.
Researchers from the University of South Australia and Flinders University found that rates of cardiovascular disease, depression, osteoporosis, diabetes and gastric disorders were higher among breast cancer survivors who had received hormonal cancer treatment than among those without breast cancer.
However, the researchers say an increased focus on healthy diets and regular exercise can play a crucial role in preventing chronic conditions post-cancer.
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Donate now to help Doctors Without Borders bring emergency medical care where it is needed most. Doctors Without Borders USA relies on unrestricted donations from private donors so when an emergency strikes we assess the needs and can act fast. Donate today.
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The News Record
Nearly one in eight women will be diagnosed with breast cancer during their lifetime, and each one of these women may have a form of breast cancer radically different from the next.
"That leads to the question, 'What is breast cancer?'" said Dr. Xiaoting Zhang, associate professor at the Department of Cancer Biology in the University of Cincinnati's College of Medicine. "Different reasons can lead to different subtypes of breast cancer — it's not like one thing can answer all of these questions."
However, a new discovery documented by Zhang's research team has identified MED1 — an estrogen receptor (ER) binding protein — as a new and important player in the complicated field of cancer biology.
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ScienceDaily
New research measures how changes in kinase activity can influence the growth, development and regulation of cancer cells. They measure kinase network rewiring that occurs in cancer patients so that they can identify new strategies for killing cancer cells.
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Cancer Network via Modern Medicine
In this video, Sarah M. Friedewald, MD, of the Northwestern Medicine Feinberg School of Medicine in Chicago, highlights recent studies advancing the field of breast cancer screening and diagnosis, including patient access to mammography and the potential need for increased surveillance in patients with false positives, as they may be at increased risk for breast cancer.
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The Journal of the American College of Surgeons
Unused prescription painkillers lying around the home have proven to be a major source of drugs supplying the nation’s opioid epidemic,1 but a new patient education brochure that describes safe disposal practices of unused pain pills can be a low-cost and effective way of getting patients to properly dispose of their leftover medications, according to study results published as an “article in press” on the website of the Journal of the American College of Surgeons ahead of print.
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| ACS CANCER PROGRAMS AND UPDATES |
ACS Quality Programs
The 2018 ACS Quality and Safety Conference: Partners in Quality will be held in Orlando, July 21-24. This education program brings health care professionals together to discuss and apply current knowledge pertaining to national and local quality initiatives in the field of surgery. Attendees will learn techniques to manage, analyze and interpret data to make a positive impact at their facilities.
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America College of Surgeons
The latest issue of the American College of Surgeons Selected Readings in General Surgery (SRGS), Surgical Infection, explores the most critical surgical approaches to controlling infection, including surgeon participation in multidisciplinary infection management teams, an enhanced understanding of emerging pathogens and resistant bacteria, timely diagnosis and effective initial therapy.
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NCDB
The National Cancer Database (NCDB) is pleased to announce that the Participant User File (PUF) application will open Jan. 22 and be open through Feb. 23. The NCDB will accept applications for site-specific files, which include cases diagnosed between 2004 and 2015. The NCDB PUF is a Health Insurance Portability and Accountability Act (HIPAA) compliant data file containing cases submitted to the Commission on Cancer's (CoC) NCDB and complies with the terms of the Business Associate Agreement between the American College of Surgeons and cancer programs accredited by the CoC; i.e., no patients or facilities can be identified. The PUF is designed to provide investigators at CoC-accredited cancer programs with a data resource they can use to review and advance the quality of care delivered to cancer patients through analyses of cases reported to the NCDB. For more information review the PUF Website. Questions regarding the NCDB PUFs or the RFA process for a PUF may be directed to NCDB technical staff at NCDB_PUF@facs.org.
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ACS-CRP
The Commission on Cancer (CoC) initiated a pilot study at 20 CoC accredited facilities in the fall of 2017 as a component of the Comparison of Operative to Monitoring and Endocrine Therapy (COMET) clinical trial (PIs: Drs. Shelley Hwang, Ann Partridge, Alastair Thompson). The study examines the risks and benefits of active surveillance compared to usual care for patients diagnosed with low risk Ductal Carcinoma in situ (DCIS), commonly known as stage 0 breast cancer. The pilot study concluded Jan. 1, 2018. Following data analysis, a CoC Special Study will be launched in spring 2018 to investigate outcomes from DCIS treatment retrospectively.
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AJCC
The American Joint Committee on Cancer (AJCC) will be exhibiting at HIMSS18 in Las Vegas, March 5-9, 2018. Make sure to visit Booth 10632 to meet the AJCC staff and learn about the API interface to access the Eighth Edition of the AJCC Cancer Staging Manual.
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NAPBC
The National Accreditation Program for Breast Centers (NAPBC) has released the 2018 NAPBC Standards Manual.
You can download a PDF of the manual by clicking the NAPBC Standards web page.
Click the 2018 NAPBC Standards Manual link at the top of the standards web page. If your browser is set to auto-download, check the downloads folder on your computer after clicking the link.
The 2018 NAPBC Standards Manual will be available online and as a PDF. The NAPBC will not have printed copies of the manual for purchase.
Please contact us at NAPBC@facs.org with any questions or comments.
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American College of Surgeons - NAPRC
The National Accreditation Program for Rectal Cancer (NAPRC) is now accept applications. The NAPRC was developed to ensure that rectal cancer patients receive appropriate care following a multidisciplinary approach. Programs will be evaluated on the standards and metrics outlined in The National Accreditation Program for Rectal Cancer Standards Manual 2017 (revised October 2017).
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The Brief
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Colby Horton, Vice President of Publishing, 469-420-2601 | Download media kit
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Disclaimer: The Brief is a digest of news selected for the Commission on Cancer (CoC) and the National Accreditation Program for Breast Centers (NAPBC), both quality programs of the American College of Surgeons, from thousands of sources by the editors of MultiBriefs, an independent organization that also manages and sells advertising. The Cancer Programs do not endorse any of the advertised products and services. Opinions expressed in the articles are those of the authors and not of the American College of Surgeons, and the Cancer Programs.
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