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| HEALTH CARE NEWS AND UPDATES |
Medical Xpress
When a RAS gene operates normally, it acts as an on/off switch for cell signaling to control cell proliferation. But when the gene mutates, the switch jams into the "on" position, allowing cells to proliferate uncontrollably.
This unstoppable cascade inevitably leads to cancer.
"The mutation in the gene is very common in pancreatic and colon cancer," said Neil Kelleher, the Walter and Mary Elizabeth Glass Professor of Chemistry, Molecular Biosciences and Medicine at Northwestern University. "But there are currently no drugs that can target the mutation and fix the broken switch."
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ScienceDaily
By studying patient colorectal tumors, a research team characterizes a fully intact protein that results from a mutation of the RAS gene, the first cancer gene ever pinpointed in human cancer cells. This finding opens the door for new targets for treatment of a gene currently thought to be "undruggable."
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Los Angeles Times
In findings with potentially broad implications for the public's health, new research has found that some women who treat their high blood pressure with a class of drugs that relaxes the blood vessels were more likely to develop pancreatic cancer than those who use other hypertension medications.
In a large and intensively studied group of middle-aged and older women, the risk of developing pancreatic cancer was more than twice as high for those who took a short-acting calcium channel blocker for more than three years.
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ExtremeTech
Google has used machine learning to solve a lot of problems like beating humans at Go and spotting exoplanets. Those are noble endeavors, but now Google Research has turned its attention to a problem that has a real impact on individual people. The company is working with doctors to develop a neural network that can identify cancer cells using an Augmented Reality Microscope (ARM). Many aspects of modern medical testing have been automated, but cancer diagnosis is still a time-consuming process.
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Our ihcDirect® method yields a revolutionary technology that opens a spectrum of new clinical applications including intraoperative surgery. Using the Novodiax PolyHRP technology, Intraoperative IHC tests can now be completed in just 10 minutes using fresh frozen tissues.
For more details, see our ihcDirect® product list.
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Medical Xpress
Researchers have long sought a treatment aimed specifically at the RAS family of genes, the most common oncogenes and those that initiate many of the most lethal tumors. However, the results of a hypothetical treatment may be far less positive than speculated, according to a manuscript published in Genes & Development by the Genomic Instability Group at the Spanish National Cancer Research Centre. The study shows that cells are capable of surviving even in the total absence of RAS genes if another gene, Erf, is also lost.
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Next Avenue
Lung cancer holds a grim distinction among malignancies: It is the No. 1 cancer killer of men and women. More people die of lung cancer than colon, breast and prostate cancers combined, according to the American Cancer Society.
Smoking is the biggest risk factor for lung cancer. In fact, smokers have a 25 times greater chance of dying of lung cancer than non-smokers, said Dr. Mara Antonoff, a thoracic surgeon at the University of Texas MD Anderson Cancer Center.
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Donate now to help Doctors Without Borders bring emergency medical care where it is needed most. Doctors Without Borders USA relies on unrestricted donations from private donors so when an emergency strikes we assess the needs and can act fast. Donate today.
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| ACS CANCER PROGRAMS UPDATES |
ACS
The 2018 American College of Surgeons Clinical Congress will not include a Cancer Liaison Program Breakfast. The Cancer Department’s Clinical Congress schedule for meetings has been streamlined this year due to space and budget limitations. The Commission on Cancer meetings that generally take place on Sunday of Clinical Congress week are scheduled to take place including the Commission on Cancer State Chair Town Hall Meeting, Commission on Cancer Executive Committee Meeting and the Commission on Cancer Annual Meeting and Cocktail Reception. The State Chair Town Hall and the Executive Committee Meetings are by invitation only. Registration to the Annual Meeting and Reception will be forthcoming. In lieu of the Cancer Liaison Program Breakfast, which traditionally occurred on Monday of Clinical Congress week, the program staff will be providing electronic media outlining important things for you to know following Clinical Congress.
Thank you for your important contributions to quality cancer care. We hope to resume this tradition in 2019.
Questions and comments can be sent to clp@facs.org.
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ACS
Registration is now open for an upcoming live webinar on coding radiation using the new radiation data items. The speakers will discuss why the changes to the radiation codes are necessary, review the codes and coding instructions, work through coding scenarios and have time for Q&A.
Space is limited and pre-registration is required.
Webinar: Coding Radiation 2018
Date: Wednesday, May 16
Time: 11 a.m. Pacific | 12 p.m. Mountain | 1 p.m. Central | 2 p.m. Eastern
Duration: 1 hour
Cost: The webinar is free of charge.
Presenters:
Robin Billet, Georgia Cancer Registry
Jim Hofferkamp, NAACCR
Kathleen Thoburn, National Cancer Database (NCDB)
CE Credit: This presentation has not been approved for CEs.
Presentation System: This live webinar will be hosted through WebEx, and audio is available through your computer or phone.
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Cancer Program- NCDB
An update to your CQIP 2017 Annual Report has been released impacting Slide 49 - Number of Major Surgical Resections for Selected Cancers, 2013 - 2015 - My Facility, “Lung Resection” includes all lung cancer resections for major surgeries (Surgical Procedure of Primary Site at This Facility / Codes 30 through 80 / NAACCR Item #670) and Slide 53 - NSCLC Resections, Unadjusted 30, 90 Day Mortality, 95 percent CI, 2013 - 2015 - My Facility vs. All CoC and CoC High Volume, changed to include only Non-Small Cell Lung (NSCLC) cases. Slides that are impacted are denoted as “Updated March 2018.” The remaining CQIP slides remain unchanged.
If you have any questions, please contact ncdbcqip@facs.org.
ACS-CRP
The Commission on Cancer (CoC) initiated a pilot study at 20 CoC-accredited facilities in the fall of 2017 as a component of the Comparison of Operative to Monitoring and Endocrine Therapy (COMET) clinical trial (PIs: Drs. Shelley Hwang, Ann Partridge, Alastair Thompson). The study examines the risks and benefits of active surveillance compared with usual care for patients diagnosed with low risk ductal carcinoma in situ (DCIS), commonly known as stage 0 breast cancer. The pilot study concluded Jan. 1, 2018. Following data analysis, a CoC Special Study will be launched in spring 2018 to investigate outcomes from DCIS treatment retrospectively.
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American College of Surgeons - NAPRC
The National Accreditation Program for Rectal Cancer (NAPRC) is now accepting applications. The NAPRC was developed to ensure that rectal cancer patients receive appropriate care following a multidisciplinary approach. Programs will be evaluated on the standards and metrics outlined in The National Accreditation Program for Rectal Cancer Standards Manual 2017 (revised October 2017).
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NAPBC
The National Accreditation Program for Breast Centers (NAPBC) has released the 2018 NAPBC Standards Manual.
You can download a PDF of the manual from the NAPBC Standards web page.
Click the 2018 NAPBC Standards Manual link at the top of the standards web page. If your browser is set to auto-download, check the downloads folder on your computer after clicking the link.
The 2018 NAPBC Standards Manual will be available online and as a PDF. The NAPBC will not have printed copies of the manual for purchase.
Please contact us at NAPBC@facs.org with any questions or comments.
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| IMPORTANT DATES AND DEADLINES |
| Date |
Event |
Location |
| June 1 |
Call for Data closes
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| July 21-24 |
ACS Quality and Safety Conference
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Orlando, FL
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| Sept. 5-7 |
2018 Cancer Programs Conference
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Chicago, IL
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| Oct. 21-25 |
ACS Clinical Congress
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Boston, MA
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The Brief
Connect with AJCC
Connect with CoC
Connect with NAPBC
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Colby Horton, Vice President of Publishing, 469-420-2601 | Download media kit
Ashley Harrington, Senior Content Editor, 469-420-2642 | Contribute news
Disclaimer: The Brief is a digest of news selected for the Commission on Cancer (CoC) and the National Accreditation Program for Breast Centers (NAPBC), both quality programs of the American College of Surgeons, from thousands of sources by the editors of MultiBriefs, an independent organization that also manages and sells advertising. The Cancer Programs do not endorse any of the advertised products and services. Opinions expressed in the articles are those of the authors and not of the American College of Surgeons, and the Cancer Programs.
American College of Surgeons
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