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More high-risk surgical patients are choosing breast reconstruction procedures after mastectomy
American College of Surgeons
The number of breast cancer patients undergoing immediate breast reconstruction operations after mastectomy has grown steadily over the past 15 years, most notably among women who were once considered too high-risk for reconstruction procedures according to new research findings published in the October 2014 issue of the Journal of the American College of Surgeons.
The team of investigators from Memorial Sloan Kettering Cancer Center, New York City, analyzed data from the National Cancer Data Base (NCDB) of the American College of Surgeons and the American Cancer Society, and looked at more than 1 million women who underwent mastectomy due to breast cancer between 1998 and 2011.
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Many lung cancer clinical trials exclude prior cancer patients
News-medical.net
Lung cancer clinical trials exclude a substantial proportion of patients due to a history of prior cancer, as shown in an analysis by cancer researchers at UT Southwestern Medical Center.
Among more than 50 lung cancer clinical trials examined, more than 80 percent excluded patients with prior cancer from participating, according to the study published in the Journal of the National Cancer Institute. The exclusion criterion was even applied in more than two-thirds of trials in which survival was not the primary endpoint.
Scientists detect early sign of pancreatic cancer
CBS News
Researchers say they've identified a sign of early development of pancreatic cancer, a leading cause of cancer death. And, they add, their discovery might lead one day to a new test to detect the disease in its initial and more treatable stages.
The early sign is an increase in levels of certain amino acids, and this occurs before patients develop symptoms and the disease is typically diagnosed.
The finding came from analyses of blood samples from 1,500 people taking part in large health-tracking studies.
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Obese in adolescence, colon cancer in later life?
HealthDay News via U.S. News & World Report
Obesity and inflammation in late adolescence are associated with increased risk for colon and rectal cancer in adulthood, a new study of Swedish males suggests.
The 35-year study found that 16- to 20-year-olds who were obese had more than twice the risk of developing colon or rectal cancer compared with normal-weight teens.
And teens with high levels of inflammation had a 63 percent increased risk of developing colorectal cancer compared with those with low levels of inflammation, researchers found.
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Two experts discuss mammography issues on The Recovery Room Show
NAPBC
The Recovery Room Show recently launched a new episode discussing the benefits and controversies surrounding mammographic screening. In the episode, host Frederick L. Greene, MD, FACS, a surgical oncologist from Charlotte, N.C., and a member of the Commission on Cancer since 2000, talks with two leading experts in the field. The show includes a discussion on common concerns with mammography, the role of insurance companies, MRIs, and a high-profile recent Canadian study that cast doubt on the abilities of the screening tool.
Driving cancer cells to suicide
Phys.org
Ludwig Maximilian University of Munich researchers report that a new class of chemical compounds makes cancer cells more sensitive to chemotherapeutic drugs. They have also pinpointed the relevant target enzyme, thus identifying a new target for anti-tumor agents.
Researchers led by LMU's professor Angelika Vollmar and professor Stephan Sieber of the Technische Universität München have identified a class of chemicals that represent a potential new weapon in the fight against malignant tumors.
Important Webinar — Caring for patients' spiritual needs: Resources for all providers
American Psychosocial Oncology Society
Plan now to join this webinar on October 24, 2014, from 2:30 – 4:00 pm Eastern Time to participate in a program that will discuss the nature of religiosity/spirituality (R/S) in cancer care, strategies for initiating conversations about patients’ R/S, and strategies for effective collaboration with healthcare chaplains. The webinar is intended for providers in all disciplines with varying degrees of experience in caring for patients with spiritual needs. For detailed information contact APOS Headquarters.
Radiation therapy for early breast cancer did not increase lymphedema risk
Oncology Practice
Directing radiation therapy to lymph nodes in the breast or chest wall as part of treatment for early node-negative breast cancer does not increase lymphedema risk, according to a secondary analysis of the National Surgical Adjuvant Breast and Bowel Project’s B-32 trial.
“There was no evidence to suggest a detrimental impact of nonregional nodal breast or chest wall radiation on the risk of lymphedema beyond surgery,” lead author Susan A. McCloskey, MD, of the University of California, Los Angeles, said at the annual scientific meeting of the American Society for Radiation Oncology.
Study: Daily dose of aspirin may cut prostate cancer risk
Bloomberg
Men who take a daily dose of aspirin or similar anti-inflammatory medicine may also reduce their risk of developing prostate cancer, researchers said.
The study, presented at an American Association for Cancer Research meeting, found that men who regularly used anti-inflammatory pain pills had a 13 percent lower risk of prostate cancer and 17 percent fewer dangerous, high-grade tumors.
Concurrent radiation and chemotherapy after surgery effective in high-risk endometrial cancer
Oncology Nurse Advisor
Endometrial cancer is the most common gynecologic malignancy. Patients with early stage disease are typically treated with surgery alone; however, patients with advanced endometrial cancer have higher instances of local or distant recurrence. Concurrent radiation and chemotherapy after surgery is used to reduce recurrence in patients with advanced disease. This study, published in the International Journal of Radiation Oncology • Biology • Physics, evaluated the efficacy and toxicity of concurrent chemoradiation with weekly paclitaxel in patients with stage III and IV endometrial cancer.
Missed last week's issue? See which articles your colleagues read most.
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The CoC Brief
Colby Horton, Vice President of Publishing, 469.420.2601
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Disclaimer: The CoC Brief is a digest of the most important news selected for the American College of Surgeons Commission on Cancer from thousands of sources by the editors of MultiBriefs, an independent organization that also manages and sells advertising. The Commission on Cancer does not endorse any of the advertised products and services. Opinions expressed in the articles are those of the author and not of the American College of Surgeons and the Commission on Cancer.
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