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Healio
With further guidance to test all cases of colorectal cancer for possible genetic markers, the FDA cleared the latest test to help distinguish between sporadic and genetic colorectal cancer, according to a release from Roche.
The Ventana mismatch repair (MMR) immunohistochemistry (IHC) test detects proteins linked to MMR – namely MLH1, MSH2, MSH6, PMS2 – and the BRAF antibody to give an indication if the patient is at risk for Lynch Syndrome.
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ACS Quality Programs
The 2018 ACS Quality and Safety Conference: Partners in Quality will be held in Orlando, July 21-24. This education program brings health care professionals together to discuss and apply current knowledge pertaining to national and local quality initiatives in the field of surgery. Attendees will learn techniques to manage, analyze and interpret data to make a positive impact at their facilities. The Cancer Programs are excited to be included in this one-of-a-kind conference and encourage staff working in CoC and/or NAPBC-accredited programs to submit an abstract for a podium or poster presentation. The abstract should relate to surgical quality improvement initiatives, including the development, implementation or validation of best practices within your accredited program. Abstracts for this conference will be accepted until Jan. 26, 2018. (Please note: This is not the 2018 Cancer Program Annual Conference that will be held in the fall of 2018. Information on the 2018 Cancer Programs Annual Conference will be available in early January 2018.)
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AJMC Managed Markets Network
For all the innovations in cancer therapy and diagnostic tools, one of the most profound advances in care may be the helping hand: the role of the nurse navigator continues to evolve, and evidence shows giving patients this source of support works.
Different aspects of the navigator and support roles were the topic of a panel on the second day of Patient-Centered Oncology Care®, the multistakeholder gathering in cancer care held in Philadelphia, Pennsylvania.
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Oxford University Press USA via ScienceDaily
A new paper in the Journal of the National Cancer Institute finds that testing for cervical cancer using HPV testing in addition to the Pap smear is unlikely to detect cancer cases that wouldn't be found using HPV testing alone.
The main goal of cervical screening programs is to detect and treat precancer before cancer develops. Cytology-based screening, known as the Pap test or Pap smear, is used to detect abnormal cells. The Pap test can also find noncancerous conditions, such as infections and inflammation.
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University of Texas M.D. Anderson Cancer Center via Medical Xpress
Research from The University of Texas M.D. Anderson Cancer Center finds adherence to surgical treatment guidelines has improved significantly among older Texas patients with colon cancer since 2001, while adherence to chemotherapy guidelines has remained largely unchanged. The study, published in Cancer, identifies factors influencing adherence rates, including socioeconomic status and access to skilled physicians.
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American College of Surgeons
The American College of Surgeons (ACS) is pleased to announce that Optimal Resources for Surgical Quality and Safety is now available for purchase. This manual is intended to serve as a trusted resource for surgical leaders seeking to improve patient care in their institutions, departments and practices. It introduces key concepts in quality, safety and reliability and explores the essential elements that all hospitals should have in place to ensure the delivery of patient-centered care. Specific topics covered include the following: the domains and phases of surgical care, peer and case review, responsibilities of the Surgical Quality Officer, institutional infrastructure, privileging and credentialing, high reliability, applications to the unique surgical disciplines, data analytics, clinical practice guidelines, quality collaboratives and education and training. The manual also includes a look at some of the “soft skills” that influence quality and safety in health care, as well as the individual surgeon’s responsibility to the patient, colleagues and the next generation of surgeons. Optimal Resources for Surgical Quality and Safety is available for $44.95 (includes shipping) for single copies (up to a quantity of nine) or $39.95 (includes shipping) for per copy for 10 copies or more on the ACS website.
Elsevier via Medical Xpress
Nonalcoholic fatty liver disease (NAFLD) is one of the more common chronic liver diseases worldwide. It is associated with metabolic syndrome (i.e., insulin resistance and diabetes) and predisposes to cardiovascular disease. In a new study published in the Journal of Hepatology, researchers identified links not only between NAFLD and hepatocellular carcinoma (HCC), which have been well established, but also to cancers outside the liver, including colorectal and breast cancer.
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Enjoy our journals? There’s an app for those! Journals such as those from the American Cancer Society ™, Journal of Surgical Oncology, Cancer Science and more are now available for your iPad and iPhone. Sample issues and abstracts, as well as open articles, can be accessed for free. A subscription to the journal is required to read the full text. Click here to learn more!
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The Medical News
Cornell researchers have taken a major step toward answering a key question in cancer research: Why is testicular cancer so responsive to chemotherapy, even after it metastasizes?
Professional cyclist Lance Armstrong, for example, had testicular cancer that spread to his lung and brain, yet he made a full recovery after conventional chemotherapy.
The key to such success appears to lie in the cancer's stem cells, which are more sensitive to chemotherapy than stem cells found in other types of cancer. Defining why testicular cancers are so susceptible to chemotherapy could eventually provide insights for treating other, more resistant cancers.
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Cancer Network via Modern Medicine
An intense dose-dense chemotherapy approach offers better survival than standard therapy, extending out to 10 years in women with breast cancer and extensive axillary lymph node involvement, according to the long-term results of the AGO study. “Dose-dense, intense dose-dense regimens or tailored dose-dense regimens have shown superior clinical outcomes when compared with conventionally dosed chemotherapy,” wrote study authors led by Volker J. Möbus, MD, of the Academic Hospital of the Goethe University Frankfurt in Germany.
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The Medical News
An unexpected finding made by a team of University of California San Diego School of Medicine researchers sheds light on the development of a new strategy for prevention of liver cancer. While studying the pathogenic mechanisms of liver cancer, the researchers discovered that a commonly used synthetic double-stranded RNA strongly boosts a variety of anti-tumor innate immune functions. They suggest it may have the potential to be administered as a vaccine to prevent cancer in individuals at high risk of developing liver cancer.
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Novodiax is soon bringing to market 10-minute fast, sensitive and simple Immunoassay (IHC) kits for in vitro diagnostic use to address unmet needs in the intraoperative surgical oncology sector. Learn More
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Cancer Programs - AJCC
The decision to delay implementation of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual, Eighth Edition to Jan. 1, 2018, provided the AJCC with an opportunity to take a careful look at the way it has traditionally communicated cancer staging. Since the manual was published last fall, the AJCC has worked with the surveillance community, the pathology community and clinical decision support software developers to take a more critical look at the content and make improvements and clarifications that will help everyone who uses this information including the registrar, clinician and the software developer.
As part of this effort, the AJCC decided to validate and update the Eighth Edition breast cancer staging system using an additional year’s worth of data from the National Cancer Database (NCDB). The AJCC Breast Expert Panel has recommended providing two breast cancer Prognostic Stage tables based on further analysis of the NCDB data.
To this end, the entire breast cancer chapter of the manual is now available through the AJCC website, and replacement pages for all updates and corrections made to the entire manual will be available in December 2017. Future printings of the Staging Manual will include the updated breast chapter as well as other minor updates and corrections issued to date.
Please visit cancerstaging.org for education and regular updates to the Eighth Edition.
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American Cancer Society via Medical Xpress
Health insurance coverage differences account for nearly one-half of the black-white survival disparity in colorectal cancer patients, according to a new study. The study, published in Gastroenterology, reinforces the importance of equitable health insurance coverage to mitigate the black-white survival disparity in colorectal cancer.
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in both men and women in the United Sates. Nonetheless, CRC incidence and mortality rates continue to be higher in blacks than in whites.
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Healio
Not every patient with early-stage breast cancer should undergo genomic testing, and oncologists should be aware of the data to inform who should and should not receive genomic testing, according to a moderator at Chemotherapy Foundation Symposium.
“Say a woman comes in to an oncologist’s office with a 2-cm tumor [that is] grade 1, node-negative and ER-positive, she probably can get away with just hormone therapy alone,” Adam M. Brufsky, MD, PhD, co-director of the comprehensive breast cancer center and associate chief of hematology/oncology at the University of Pittsburgh, told HemOnc Today. “This is something we have to think about. Instead of just doing the tests all the time on everybody, we should be more judicious [about who we test].”
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Doctors Without Borders/Médecins Sans Frontières (MSF) is actively recruiting general and trauma surgeons with experience in emergency obstetrics for international missions in developing countries. Learn more.
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The Brief
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Colby Horton, Vice President of Publishing, 469-420-2601 | Download media kit
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Disclaimer: The Brief is a digest of news selected for the Commission on Cancer (CoC) and the National Accreditation Program for Breast Centers (NAPBC), both quality programs of the American College of Surgeons, from thousands of sources by the editors of MultiBriefs, an independent organization that also manages and sells advertising. The CoC and NAPBC do not endorse any of the advertised products and services. Opinions expressed in the articles are those of the author and not of the American College of Surgeons, the CoC and the NAPBC.
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