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University of Illinois at Urbana-Champaign via Medical Xpress
The lining of the intestines — the epithelium — does more than absorb nutrients from your lunch. It grows, shrinks and adjusts the very makeup of its cells in response to whatever you just ate. And understanding that process might just give scientists new insights into the behavior of cancer cells. The ability of the intestinal lining to respond to your food depends on stem cells tucked down in tiny crypts along the epithelium. Certain cues cause stem cells to grow more epithelium, to be able to handle a higher volume of food coming in.
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ACS Cancer Programs
The American College of Surgeons (ACS) Cancer Programs (ACS Clinical Research Program, American Joint Committee on Cancer, Commission on Cancer, National Accreditation Program for Breast Centers, and National Cancer Database) is requesting your input regarding your and your staff’s educational needs. Please take a few minutes to complete the Cancer Programs Educational Needs Survey by Monday, Dec. 4, 2017. The Cancer Programs appreciate your participation. The information provided will be used to guide the Cancer Programs development of future educational programs.
The JAMA Network
In this study of 1,869 patients with tumor blocks of resected stage III colon cancer, for those patients with RAS mutant or BRAF mutant genotype, disease-free survival was better with right- vs left-sided tumors; for patients who had RAS and BRAF double wild type, disease-free survival was worse in those with right-sided tumors. No predictive effect of sidedness for cetuximab efficacy was found.
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Modern Healthcare
At St. Elizabeth Medical Center in Utica, New York, the CMS' Hospital Reduction Readmissions Program was an expensive wake-up call to hospital leaders that they needed to do a better job of preventing patients from making a U-turn after being discharged. The hospital was hit with a $397,153 penalty in 2013, the first year the CMS issued penalties under the program, according to a data analysis by Leavitt Partners.
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ACS CRP
The Alliance/American College of Surgeons Clinical Research Programs (ACS CRP) has introduced a series of webinars focused on clinical trials to engage investigators and study staff. To date, two webinars (Breast and Lower GI) have been held. If you were not able to view these live, you can access the recordings from the Clinical Research Program Investigator Webinars website. Watch the website and the Important Dates and Deadlines section of the Brief for future titles and dates.
Modern Medicine via Cancer Network
The use of duloxetine resulted in reduced aromatase inhibitor (AI)-associated musculoskeletal symptoms compared with placebo in women with early-stage breast cancer, according to a new study. However, the agent did result in more low-grade toxicity. Duloxetine, a serotonin–norepinephrine reuptake inhibitor, is indicated for depression and anxiety, but also for treatment of multiple chronic pain conditions, including fibromyalgia and chronic musculoskeletal pain. The investigators conducted a randomized phase III trial comparing duloxetine with placebo in postmenopausal women with early breast cancer undergoing AI treatment
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ACS-AJCC
Register now for the live AJCC Staging Manual Eighth Edition for registrars on Introduction & Descriptors, which will provide information to demonstrate purpose and approach to AJCC staging, outline use of stage descriptors and guidelines and dissect the 8th edition one-page guide. Future webinars are scheduled as follows: Feb. 15, 2018 -Minor Rule Changes; March 20, 2018 - Major Rule Changes; April 17, 2018 - CAnswer Forum & Staging Questions; July 25, 2018 - Head and Neck Staging; Sept. 6, 2018 -Breast Staging. All webinars will be held from 1:00-2:00 p.m. CT. Make sure to mark your calendars. Additional information and registration links coming soon. Earn free Category A CE credits for the live or recorded webinars. Visit the AJCC website for updates.
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PRODUCT SHOWCASE | Advertisement
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Enjoy our journals? There’s an app for those! Journals such as those from the American Cancer Society ™, Journal of Surgical Oncology, Cancer Science and more are now available for your iPad and iPhone. Sample issues and abstracts, as well as open articles, can be accessed for free. A subscription to the journal is required to read the full text. Click here to learn more!
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Medical News Today
People undergoing cancer treatment often report experiencing "chemo brain," or states of confusion and cognitive impairment due to aggressive chemotherapy treatment. But new research suggests that these cognitive problems might start earlier, with the development of cancer tumors. Researchers at the Baycrest Centre for Geriatric Care in Toronto, Canada, conducted a study focusing on the "chemo brain" effect, with the purpose of understanding to what extent these states of cognitive impairment are caused by the treatment.
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ACS
Realize the potential of your profession and become an Affiliate Member of the American College of Surgeons. Affiliate members receive a variety of member benefits, including:
- Free, online access to the Journal of the American College of Surgeons and the Bulletin of the American College of Surgeons
- Access to practice management and patient education resources
- Discounted rates for ACS educational programs and products, including the annual Clinical Congress
- Participation in the ACS-sponsored insurance programs
- Access to an online Community of other Affiliate Members
- Access to the members-only side of the ACS website at facs.org
Here’s what you’ll need to apply: your current contact information, information about your current employment, details about your education and certification and a reference from a Fellow of the American College of Surgeons.
The Affiliate Member application fee is $50, which covers your first year of membership. Annual dues are then $100 annually. Join the more than 80,000 members who are shaping the future of surgical care. Join today! For questions, contact enroll@facs.org.
Oncology Nurse Advisor
Loratadine was effective in preventing pegfilgrastim-associated mild to moderate bone pain when administered prophylactically to women with breast cancer receiving chemotherapy, a study published in Supportive Care in Cancer has shown.
Bone pain is a commonly occurring adverse event among patients with cancer who receive pegfilgrastim as supportive therapy to chemotherapy and may lead to discontinuation of treatment. This in turn may cause increased rates of infection, hospitalization and mortality.
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Novodiax is soon bringing to market 10-minute fast, sensitive and simple Immunoassay (IHC) kits for in vitro diagnostic use to address unmet needs in the intraoperative surgical oncology sector. Learn More
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University of Illinois at Urbana-Champaign via ScienceDaily
A drug that spurs cancer cells to self-destruct has been cleared for use in a clinical trial of patients with anaplastic astrocytoma, a rare malignant brain tumor, and glioblastoma multiforme, an aggressive late-stage cancer of the brain. This phase Ib trial will determine if the experimental drug PAC-1 can be used safely in combination with a standard brain-cancer chemotherapy drug, temozolomide.
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ACS Quality Programs
The 2018 ACS Quality and Safety Conference: Partners in Quality will be held in Orlando, July 21-24. This education program brings health care professionals together to discuss and apply current knowledge pertaining to national and local quality initiatives in the field of surgery. Attendees will learn techniques to manage, analyze and interpret data to make a positive impact at their facilities. The Cancer Programs are excited to be included in this one-of-a-kind conference and encourage staff working in CoC and/or NAPBC-accredited programs to submit an abstract for a podium or poster presentation. The abstract should relate to surgical quality improvement initiatives, including the development, implementation or validation of best practices within your accredited program. Abstracts for this conference will be accepted until Jan. 26, 2018. (Please note: This is not the 2018 Cancer Program Annual Conference that will be held in the fall of 2018. Information on the 2018 Cancer Programs Annual Conference will be available in early January 2018.)
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The Medical News
A small protein modification can trigger the aggressive migratory and invasive properties of prostate cancer cells, according to new research published on the cover of Oncotarget. The findings give greater insight into how cancers can move from one location in the body to another, and could help develop more effective therapies in the future.
When cells break free from the original tumor and migrate to another location through the bloodstream, they become metastatic. The emergence of secondary tumors is often correlated with a poor prognosis.
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American College of Surgeons
Healio
Primary prevention of colorectal cancer through the removal of adenomatous polyps led to greater mortality reductions than early detection of the disease, according to an analysis of data from the PLCO cancer screening trial.
Thus, colorectal cancer screening guidelines should emphasize the importance of primary prevention, according to the researchers. Previous randomized controlled trials have indicated flexible sigmoidoscopy effectively reduces colorectal cancer incidence and mortality.
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Doctors Without Borders/Médecins Sans Frontières (MSF) is actively recruiting general and trauma surgeons with experience in emergency obstetrics for international missions in developing countries. Learn more.
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The Brief
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Colby Horton, Vice President of Publishing, 469-420-2601 | Download media kit
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Disclaimer: The Brief is a digest of news selected for the Commission on Cancer (CoC) and the National Accreditation Program for Breast Centers (NAPBC), both quality programs of the American College of Surgeons, from thousands of sources by the editors of MultiBriefs, an independent organization that also manages and sells advertising. The CoC and NAPBC do not endorse any of the advertised products and services. Opinions expressed in the articles are those of the author and not of the American College of Surgeons, the CoC and the NAPBC.
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