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Medscape
An unexpected finding in women with estrogen receptor-positive metastatic breast cancer is the emergence of acquired mutations in HER2.
These mutations explain some of the resistance to hormone-directed therapy that is seen in these patients, and the new finding could offer a new approach to clinical management, researchers said at a media preview for the American Association for Cancer Research 2018 Annual Meeting.
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DARK Daily
Anatomic pathologists working for reference laboratories can now provide diagnostic services to hospitals, critical-access hospitals and ambulatory care facilities in the U.S. based on the organization's Clinical Laboratory Improvement Amendments status, rather than the usual credentialing and privileging. The Joint Commission made the change effective January 2018.
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University of Chicago Medical Center via ScienceDaily
Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome and acute myeloid leukemia. Unfortunately, most patients treated with epigenetic modifying drugs develop resistance, resulting in therapeutic failure and eventually, patient death. The mechanisms underlying the selectivity and resistance of epigenetic modifying drugs remain largely elusive.
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NPR
When Health and Human Services Secretary Margaret Heckler announced that scientists had discovered the virus that caused AIDS at a press conference in 1984, the disease was still mysterious and invariably fatal.
Perhaps with a vaccine, AIDS could be ended like smallpox or contained like polio, two scourges that yielded to intense public health interventions. Heckler suggested that experimental vaccine trials were just two years away.
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Medical News Today
Breaking research published in the journal Nature describes a new anti-cancer protein. The finding could help to spot cancer earlier and treat it more effectively.
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Infection Control Today
School closure is often considered as an option to mitigate influenza epidemics because of its potential to reduce transmission in children and then in the community. The policy is still however highly debated because of controversial evidence. Moreover, the specific mechanisms leading to mitigation are not clearly identified.
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The Conversation
More women are affected by HIV than any other life-threatening infectious agent. This makes it crucial to identify all factors increasing the risk of HIV infection.
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To find out how to feature your company in the ASCLS eNewsletter and other advertising opportunities, Contact James DeBois at 469-420-2618.
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SeraSub® is a synthetic serum for use as a component in preparing standards and controls for in-vitro diagnostic tests. Learn more
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Nature
Dieter Egli was just about to start graduate school in 1998 when researchers first worked out how to derive human embryonic stem cells. In the two decades since, the prolific cells have been a fixture of his career.
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