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NIH/National Institute of Allergy and Infectious Diseases via Infection Control Today
A near-atomic level map of Zika virus shows its structure to be largely similar to that of dengue virus and other flaviviruses, but with a notable difference in one key surface protein, report scientists funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The variation in the Zika envelope (E) glycoproteins — 180 of which are packed on the virus's outer shell — may provide clues to better understand how Zika virus enters human cells and suggests ways to combat the virus with drugs or vaccines aimed at the newly detailed region.
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Chemistry World
A potential laboratory-acquired infection at the U.S. Centers for Disease Control was announced March 31, following several similar failures at the agency and other U.S. government research bodies.
The CDC is currently investigating whether one of its workers diagnosed with a salmonella infection acquired it at a lab where research is undertaken on common and treatable pathogens.
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NPR
When a Connecticut woman who was HIV-positive died earlier this month, her family decided to donate her organs to others who needed them.
Doctors in Maryland announced that they performed two landmark, successful surgeries with her kidney and liver — transplanting the organs to HIV-positive patients.
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HealthDay News
As the continental United States braces itself for the Zika virus, federal, state and local health officials gathered in Atlanta to prepare for the upcoming mosquito season.
More than 300 public health experts attended the Zika Action Plan Summit, hosted by the U.S. Centers for Disease Control and Prevention and intended to help ensure a coordinated response to the mosquito-borne illness.
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Medical News Today
Tissue engineering of skin has come a long way in recent years, but it is struggling to progress from growing simple 2-D sheets of tissue cells to regenerating a functioning, complex 3-D organ complete with hair follicles, glands and connections to other organ systems. Now, a new study — by researchers in Japan and published in the journal Science Advances — appears to have made a significant step forward in skin bioengineering and regenerative medicine.
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PRODUCT SHOWCASE
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ZeptoMetrix Corporation (ZMC) is an Industry leader and innovator identified with quality, reliable and trusted Products and Services for Infectious Disease Diagnostic Development. From assay conception to launch, our Scientific and Operational Teams provide our Customers with cohesive, inventive and cost effective solutions.
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University of Arkansas via Lab Manager
A research team led by University of Arkansas chemist Jingyi Chen and University of Arkansas for Medical Sciences microbiologist Mark Smeltzer has developed an alternative therapeutic approach to fighting antibiotic-resistant infections.
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HealthDay News via U.S. News & World Report
Defitelio (defibrotide sodium) has been approved by the U.S. Food and Drug Administration to treat a rare, but usually fatal liver disease that affects some people who have had a stem cell transplant.
The condition, fatal in as many as 80 percent of cases, is called hepatic veno-occlusive disease. It affects people who have had a stem cell transplant to treat cancers of the blood or bone marrow.
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Reuters
A stem cell therapy developed by Vericel Corp. helped reduce deaths and hospitalizations in advanced heart failure patients, according to data from a midstage study, potentially providing a treatment that could delay the need for heart transplants. The data compared Vericel's bone marrow-derived ixmyelocel-T stem cells with placebo in 109 well-treated patients with advanced ischemic heart failure who had exhausted optimal medical and device therapies.
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National Centre for Biological Sciences via ScienceDaily
Scientists have elucidated genome-wide patterns in the complex structures formed by the DNA of bacteria in different environmental conditions. These complex structures in DNA could be playing important roles in regulating gene expression.
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