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Carnegie Mellon University via ScienceDaily
Researchers have developed a new method for preparing mesenchymal stem cells that not only leads to the production of more native stem cells, but also labels them with a Food and Drug Administration-approved iron-oxide nanoparticle. The technology could allow researchers to track the cells in vivo using magnetic resonance imaging during preclinical and clinical trials.
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The Scientist
The International Society for Stem Cell Research released an update to its guidelines, calling for research institutions to construct oversight committees to handle stem cell and embryo research conducted by their scientists. The move appears to be an attempt to get out in front of federal regulations that may restrict or complicate genome editing in human embryos.
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Rutgers University via Infection Control Today
An oral drug used to treat an illness unrelated to HIV eradicated infectious HIV-producing cells in lab cultures while sparing uninfected cells — and suppressed the virus in patients during treatment and for at least eight weeks after the drug was stopped, according to results of a clinical pilot trial and researchers at Rutgers University and Dartmouth College.
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Memorial Sloan Kettering Cancer Center via ScienceDaily
The lack of participation in clinical research may be the Achilles' heel of today's cancer community. According to a new survey of more than 1,500 consumers and nearly 600 physicians, only 35 percent of Americans indicated that they were "likely" to enroll in a clinical trial. Other studies have shown that only 4 percent of cancer patients enroll in clinical trials nationally each year.
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Fox News
Pfizer Inc.'s Ibrance, in combination with another commonly used drug, kept advanced breast cancer in check significantly longer than the standard treatment alone in a late stage study, according to data released recently.
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Health Canal
A laboratory blood test developed at John Hopkins for the diagnosis of a rare genetic red blood cell disorder also shows promise in identifying HELLP syndrome, a life-threating high blood pressure condition affecting 1 percent of all pregnant women that causes hypertension along with end organ damage, researchers report.
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National Institute of Health via Lab Manager
A viral protein known as NS5 is a promising target for vaccines against Zika and related viruses, according to National Institutes of Health scientists and colleagues at Mount Sinai's Icahn School of Medicine. Their study, published online May 19 in Cell Host & Microbe, suggests that altering or removing the NS5 protein from Zika virus would allow the human body's own immune defenses to attack the virus.
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Scientific American
Drug dosing is all about balance. Doctors need to prescribe enough of a drug to treat the problem, but now so much as to cause toxicity or other issues. Now, simple genetic tests can help them hit that sweet spot.
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Reuters
The U.S. House of Representatives passed a bill to provide $622.1 million to control the spread of Zika virus, far below President Barack Obama's request and lower than Senate legislation. The bill passed the Republican-controlled House 241 to 184, largely along party lines, and sets up a confrontation with both the Republican-majority Senate and Democratic Obama administration.
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DARK Daily
Point-of-care testing and remote patient monitoring are two technologies that could be disruptive to the clinical laboratory industry, particularly if use of these devices was to reduce the volume of patient specimens that are referred to the nation's large, centralized medical laboratories. This is one reason why savvy pathologists watch the stream of new products designed to allow athletes and consumers to monitor their fitness and other characteristics of good health.
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