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Sanford-Burnham Prebys Medical Discovery Institute via ScienceDaily
Scientists have made a major advance in understanding how the cells of an organism, which all contain the same genetic information, come to be so diverse. A study shows that a protein called OCT4 narrows down the range of cell types that stem cells can become. The findings could impact efforts to produce specific types of cells for future therapies to treat a broad range of diseases.
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Johns Hopkins Medicine via Lab Manager
By creating a cell model of medulloblastoma from human cells rather than working with mouse cells, the researchers say they can be more confident that patients' response to the drugs identified in the screenings may be more comparable to humans.
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Ars Technica
The National Institutes of Health has announced that it is revising the rules that govern its funding of stem cell research. The rules focus on cases where human stem cells are introduced into embryonic animals, creating an embryo that's a mixture of human and animal tissues.
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Reuters
A type of experimental vaccine that can be made has protected mice against influenza, Ebola and Zika viruses may offer promise for quick responses to disease outbreaks in people, according to Massachusetts Institute of Technology researchers.
MIT scientists said their vaccines, still in early developmental stages, harness messenger RNA, a genetic material that can be programmed to fight any viral, bacterial or parasitic disease by provoking an amplified immune response in the body.
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Medical News Today
New research published in PLOS Genetics provides evidence that alcoholism has a genetic influence, after uncovering hundreds of genes that may increase the desire to consume alcohol. Alcohol use disorders remain one of the leading causes of preventable death in the United States, responsible for around 88,000 deaths every year.
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U.S. Military HIV Research Program via Infection Control Today
The Walter Reed Army Institute of Research, in collaboration with the Beth Israel Deaconess Medical Center and Harvard Medical School, has completed a second round of preclinical studies on a promising Zika vaccine candidate and found it to completely protect rhesus monkeys from experimental infection with Zika virus.
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Genetic Engineering & Biotechnology News
The breast is a microenvironment. It consists of epithelium, stroma and a mucosal immune system. It is also home to a collection of microbes. Call them partners, bystanders or interlopers, these microbes are actually community members.
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Institute of Cancer Research via ScienceDaily
Genetic testing of patients with a rare form of cancer that can affect children and young adults can pick out genetic errors hidden in their family tree that increase the risk of a wide variety of cancer types.
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Give your health system access to CLSI’s full library of documents, including EP23, the best source for IQCP guidance.
Visit http://clsi.org/health-system to learn more.
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Cornell Chronicle
A vaccine developed at Weill Cornell Medicine and NewYork-Presbyterian to blunt the effects of cocaine has advanced to clinical trials for testing in humans. After demonstrating that the vaccine prevented cocaine from reaching the brain in earlier animal studies, investigators are now enrolling active cocaine addicts in a randomized control study to test how it works in people.
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DARK Daily
Even as pathologists, clinical laboratories and other medical service providers adapt to value-based care initiatives and bundled payment plans, health systems are looking for ways to optimize both quality of care and treatment costs. In some cases, this is the reason behind new joint ventures between provider and payer organizations.
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