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More egg recalls could be ahead, FDA chief says More egg recalls could be ahead, FDA chief says Share      The recall of more than half a billion eggs over the past two weeks is the "largest such egg recall in recent history" and the Food and Drug Administration "may need to continue with smaller subrecalls," FDA Commissioner Margaret Hamburg said on CNN's "American Morning." Hillandale Farms of Iowa announced it was recalling more than 170 million eggs. Another 380 million have been recalled by another Iowa producer, Wright County Egg, after the FDA linked the eggs to an outbreak of salmonella that has sickened hundreds of people nationwide. More
New troponin recommendations should bridge gap between lab and clinic Heartwire via Medscape Share
Cardiac troponin is a "crucial marker" of acute MI and should be used for risk stratification, but it can also be released in clinical conditions other than AMI, say Dr. Kristian Thygesen (Aarhus University Hospital, Denmark) and colleagues, who have published new recommendations on how doctors should use troponin to guide cardiac care. The guidance is the first in a series of three on biomarkers, Thygesen told heartwire , with other documents on B-type natriuretic peptide (BNP) and C-reactive protein (CRP) due to follow from the same European Society of Cardiology Working Group on Acute Cardiac Care. "Clinicians do not fully understand how to handle troponin, so we developed this to help them. This is designed to fill in the vacuum between the lab people and clinicians," he explained. More More community hospital pathology laboratories are ready to tackle molecular testing for infectious disease and cancer DARK Daily Share
Because of advances in automated molecular systems and less complex technologies, it is now possible for more clinical pathology laboratories in community hospitals to establish their own molecular diagnostics testing program. This is particularly true of testing for infectious disease and cancer. At the same time that local pathology and clinical laboratories have this opportunity to provide useful new molecular and genetic tests to physicians in their community, questions often remain about how to assess the clinical value of performing a molecular diagnostic test versus the cost of performing that assay. More Ovarian cryopreservation may be unsafe in leukemia patients Medscape Medical News Share
Ovarian tissue cryopreservation is a relatively new option for cancer patients who wish to preserve fertility prior to undergoing chemotherapy and radiotherapy. But even though autotransplantation of frozen–thawed ovarian tissue harvested before chemotherapy/radiotherapy has thus far led to 13 live births, a serious risk might accompany this procedure. In a report published online in Blood, researchers believe that this method of fertility preservation might be unsafe for patients with leukemia. The risk is that the reimplanted tissue might harbor malignant cells that could induce disease recurrence. More
Killer T-cells, the fix for organ rejection? New Scientist magazine Share
A convenient type of killer white blood cell could make organ rejection a thing of the past. The cells suppress the immune response in the livers of mice, without affecting the rest of the immune system. Humans have this type of blood cell, so it might be possible to create immune-tolerant organs for transplant. More Researchers discover cause of immune system avoidance of certain pathogens Infection Control Today Share
A special set of sugars found on some disease-causing pathogens helps those pathogens fight the body's natural defenses as well as vaccines, say two Iowa State University researchers. This discovery may be a first step in understanding a disease family that includes tuberculosis for which there are currently no good vaccines or cures. Nicola Pohl, professor of chemistry, and Christine Petersen, assistant professor of veterinary pathology, discovered that a natural coating of sugar interacts with the body's defense cells to dampen its own immune response. Their findings are published in the current online issue of the Journal of the American Chemical Society. More Multiple myeloma: Laboratory testing for plasma cell proliferative processes Clinical Laboratory News Share
Although it's not widely known today, multiple myeloma was the first disease for which the clinical laboratory could measure a quantifiable tumor marker, the Bence Jones protein. First described in 1847 by the English physician Henry Bence Jones and later characterized as a monoclonal free immunoglobulin light chain (mFLC), the Bence Jones protein and related monoclonal protein markers are invaluable for detecting, classifying, staging, and monitoring multiple myeloma. More
Newly identified RNA sequence is key in microRNA processing Science Daily Share
Researchers at Tufts University School of Medicine and Tufts Medical Center have identified an RNA sequence that promotes increased numbers of specific microRNAs (miRNAs), molecules that regulate cell growth, development, and stress response. The discovery helps researchers understand the links between miRNA expression and disease, including heart disease and cancer. More Pesticide exposure linked to ADHD risk WebMD Health News Share
Exposure in the womb to pesticides known as organophosphates may increase the chance that children, especially boys, will develop attention problems by age 5, a study shows. The research is published in Environmental Health Perspectives. Researchers followed more than 300 children who took part in the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) study. It was designed to look at how exposure to organophosphate pesticides affects reproductive health. More |
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