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August 29, 2017

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New way to treat HIV identified

University of Southern California via ScienceDaily
Medical treatment that targets human proteins rather than ever-mutating viruses may one day help HIV-positive people whose bodies have built a resistance to "cocktails" currently used to keep them healthy. Now researchers have pinpointed a protein variant that can be targeted to prevent the human immunodeficiency virus from harming HIV-positive individuals. READ MORE

Lab-made 'mini organs' helping doctors treat cystic fibrosis

Pharmaceutical Processing
Els van der Heijden, who has cystic fibrosis, was finding it ever harder to breathe as her lungs filled with thick, sticky mucus. Despite taking more than a dozen pills and inhalers a day, the 53-year-old had to stop working and scale back doing the thing she loved best, horseback riding. READ MORE

Researchers use antibiotics combination to kill 1st strain of highly resistant E. coli in US

University at Buffalo via Infection Control Today
The golden age of antibiotics may be drawing to a close. The recent discovery of E. coli carrying mcr-1 and ndm-5 — genes that make the bacterium immune to last-resort antibiotics — has left clinicians without an effective means of treatment for the superbug. But in a new study, University at Buffalo researchers have assembled a team of three antibiotics that, together, are capable of eradicating the deadly bacterium. READ MORE

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Scientists uncover stem cell response to prolonged irradiation

News-Medical.Net
Researchers from several Russian institutes, including MIPT, have found out how prolonged exposure to ionizing radiation affects human stem cells. They discovered that it causes a cell cycle delay, which leads to faster repairs of radiation-induced DNA double-strand breaks, with fewer errors. It is unclear what the health implications are, particularly how this affects the risk of developing cancer. READ MORE

Clinical laboratories may need to expand test portfolios with companion and complementary diagnostic assays as more test-dependent drug therapies enter market

DARK Daily
Companion diagnostics are well-known to medical laboratorians. However, the new-breed of complementary diagnostics might not be as familiar. As the pharmaceutical pipeline increasingly becomes filled with test-dependent new drug therapies, medical laboratories and anatomic pathology groups may need to sharpen their understanding of companion and complementary diagnostics to broaden their laboratory test portfolios and keep pace with the growing demand for these new diagnostics. READ MORE

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Researchers develop faster, more accurate test for liver cancer that can be administered anywhere

University of Utah via ScienceDaily
A rapid portable screening test for liver cancer has been created that doesn't involve sending a specimen to a blood lab and cuts the wait time for results from two weeks to two minutes. This inexpensive test can be administered wherever the patient is, which will be valuable for developing nations with little access to hospitals. READ MORE

New vaccine could someday fight the effects of opioid combinations

American Chemical Society via Lab Manager
Substance abuse is a continuing problem in the U.S., particularly with heroin and other opioids, to the point of being an epidemic. Treatments exist, but far too often patients relapse with devastating impacts on themselves and those around them. Now, scientists report that they have made progress toward a vaccine against the effects of fentanyl, a synthetic opioid, in combination with heroin. READ MORE

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What's happened to Zika? Is the outbreak in the Americas over?

Outbreak News Today
In early 2015, a mosquito-borne virus that few people heard of began its spread through the immunologically naive population of Latin America and the Caribbean. In 2016, 5,102 cases were reported in the U.S., including 224 locally acquired. There were 36,079 cases reported in U.S. territories. READ MORE