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September 12, 2017

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Early immune response provides insight into Ebola vaccination

Infection Control Today
The latest outbreaks of emerging, dangerous pathogens, such as Ebola, MERS-CoV or Zika, emphasise the importance of the rapid development of effective vaccines. However, being able to predict the efficacy of new vaccines is and remains a challenge in vaccine development. READ MORE

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Vaccine to prevent most cervical cancers shows long-term effectiveness

University of Alabama at Birmingham via Lab Manager
A vaccine that can literally eradicate the majority of cervical cancer cases shows long-term effectiveness in a study published Sept. 5 in The Lancet. This study of 14,215 women in 18 countries extends and solidifies the initial phase 3 efficacy and safety trial of the nine-valent human papilloma virus vaccine, Gardasil 9, that was published in February 2015 in The New England Journal of Medicine. READ MORE

Sleep apnea wreaks havoc on your metabolism

HealthDay News
People who leave their sleep apnea untreated for just a short time may face a higher risk of spikes in blood sugar levels, stress hormones and blood pressure, a new study finds. Even a few days of failing to treat sleep apnea can cause these levels to go up, researchers found. They say the findings support the ongoing use of continuous positive airway pressure devices to protect sleepers from airway closure due to sleep apnea. READ MORE

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Antidepressants could delay Parkinson's progression

Medical News Today
A 50-year-old antidepressant could stop the buildup of a brain protein involved in Parkinson's disease, marking a discovery that could bring us closer to slowing the condition. A new study led by researchers from Michigan State University in Grand Rapids found that people treated with tricyclic antidepressants were less likely to require drug treatment for Parkinson's disease. READ MORE

Study: Zika virus could be used to treat brain cancer patients

Rockefeller University Press via ScienceDaily
Recent outbreaks of Zika virus have revealed that the virus causes brain defects in unborn children. But researchers now report that the virus could eventually be used to target and kill cancer cells in the brain. READ MORE

Researchers develop Lassa fever treatment effective 8 days after infection

Infection Control Today
A collaborative team of scientists, led by a group at the University of Texas Medical Branch at Galveston, has successfully protected nonhuman primates against one of the most deadly viruses in the world, Lassa fever, eight days after they became infected. The findings are now available in Nature Medicine. READ MORE

Human skin cells transformed directly into motor neurons

Washington University in St. Louis via ScienceDaily
Scientists have converted skin cells from healthy adults directly into motor neurons without going through a stem cell state. The technique makes it possible to study motor neurons of the human central nervous system in the lab. Unlike commonly studied mouse motor neurons, human motor neurons growing in the lab would be a new tool since researchers can't take samples of these neurons from living people but can easily take skin samples. READ MORE

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The bacteria responsible for Legionellosis modulates the host cell metabolism to its advantage

Infection Control Today
Intracellular pathogens adopt various strategies to circumvent the defenses of the host cell and to proliferate intracellularly. One specific strategy is to target host organelles like the mitochondria. Mitochondria are well-defined cytoplasmic organelles, which take part in a variety of cellular metabolic functions. READ MORE

Hospitals, pathology groups, clinical labs struggling to collect payments from patients with high-deductible health plans

DARK Daily
Rising out-of-pocket costs for healthcare consumers is translating into increasing amounts of red ink for hospitals and healthcare providers struggling to collect bills from patients with high-deductible health plans. Clinical laboratories and pathology groups are unlikely to be immune from these challenges, as increasing numbers of patients with smaller healthcare debts also are failing to pay their bills in full. READ MORE