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Medical News Today
A new study has investigated how mothers and fathers cause new genetic mutations in their children, and how some of these mutations may lead to negative outcomes.
Characteristics that we inherit from our parents — starting with very basic features such as eye color or hair texture — shape not just our identity, but also the state of our health, both earlier and later in life.
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Washington University School of Medicine via Lab Manager
There's good fat and bad fat in our bodies. The good fat helps burn calories, while the bad fat hoards calories, contributing to weight gain and obesity. Now, new research at Washington University School of Medicine in St. Louis has identified a way to convert bad, white fat into good, brown fat, at least in mice.
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ZeptoMetrix Corporation (ZMC) is an Industry leader and innovator identified with quality, reliable and trusted Products and Services for Infectious Disease Diagnostic Development. From assay conception to launch, our Scientific and Operational Teams provide our Customers with cohesive, inventive and cost effective solutions.
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R&D Magazine
New treatments have emerged to temporarily prevent stem cells from dying during hematopoietic stem cell transplants.
Researchers from the University Medical Center of Freiburg in Germany have taken a new approach to allow those needing transplants, including those suffering from leukemia and lymphoma, to be treated using fewer donor stem cells while limiting potential side effects.
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DARK Daily
Any day now, Medicare officials will announce the Medicare Part B Clinical Laboratory Fee Schedule for 2018. Both the Centers for Medicare and Medicaid Services and the Department of Health and Human Services Office of Inspector General have issued reports indicating that these fee cuts will total $400 million just during 2018.
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Infection Control Today
Solitary animals called tayra might look pretty harmless, but some may actually be incubators for a parasite that causes Chagas disease, a chronic, debilitating condition that is spread by insects called kissing bugs and affects more than 8 million people worldwide. In a study published in the journal Peer, researchers from the University of California, Riverside have identified several new hosts for parasite-spreading kissing bug species, including tayras, new world monkeys, sloths, porcupines and coatis — which are the South American cousins of raccoons.
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The LIAISON® Treponema assay is your solution for automating syphilis testing. Improve sensitivity and specificity over RPR screening using our fully-automated LIAISON® XL platform. The LIAISON® Treponema assay detects both IgG and IgM antibody response to T. pallidum infections. Visit www.diasorin.com for more information.
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University of California, Berkeley via ScienceDaily
A detailed study of how domains within the Cas9 protein move when the molecule binds to DNA has allowed scientists to locate the protein that monitors the fidelity of binding between the Cas9 single-guide RNA and its DNA target. The researchers then tweaked this domain to boost specificity, creating the highest fidelity Cas9 protein to date.
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Science Magazine
For about $75, the governments in South Africa and Kenya will soon be able to treat an HIV-infected person for one year with a pill taken once a day that contains a "best-in-class" combination of three anti-retroviral drugs. The backbone of the new pill is dolutegravir, a remarkably powerful and safe anti-retroviral that inhibits HIV's integrase enzyme and has been too expensive for most poor and middle-income countries to afford.
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Reuters
British scientists have used a genome editing tool known as CRISPR/Cas9 to knock out a gene in embryos just a few days old, testing the technique's ability to decipher key gene functions in early human development.
The researchers said their experiments, using a technology that is the subject of fierce international debate because of fears that it could be used to create babies to order, will deepen understanding of the biology of early human development.
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