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Society calls for stronger FDA science investment to better fight neglected diseases Infection Control Today Share     U.S. scientists committed to finding answers to reducing and eliminating what are known as neglected tropical diseases that plague the world's poorest people in developing countries, urged the FDA to include in its orphan classification the neglected infections of poverty that also affect Americans, and expressed support for stronger relationships with the FDA to ultimately halt these ancient scourges. In testimony presented at the FDA hearing, Advancing the Development of Medical Products Used in the Prevention, Diagnosis, and Treatment of Neglected Tropical Diseases, Peter J. Hotez, MD, PhD, and president-elect of the American Society for Tropical Medicine and Hygiene, offered recommendations for the FDA's consideration that based on its unique regulatory and public health role could position the agency to more effectively address these diseases and conditions. More
Cell find could boost cancer fight UKPA via The Press Association Share
A discovery about the behavior of cells in the intestine could help efforts to treat bowel cancer, a charity has said. Cancer Research U.K. scientists found that gut stem cells replace themselves in a completely different way from previously held theories. It was thought stem cells in the gut replaced each other according to a predetermined, hierarchical system which meant only a handful of stem cells were able to produce the many different types of stem cells in that part of the body. More Biomarkers in cerebrospinal fluid discriminate between dementias Medscape Medical News Share
Combining biomarkers from cerebrospinal fluid is helping researchers identify and distinguish between dementia with Lewy bodies and Alzheimer's disease. Presenting at the American Neurological Association 135th Annual Meeting, investigators showed that patterns of β-amyloid 42 and α-synuclein in cerebrospinal fluid appeared to differ between these conditions. "Our study supports the hypothesis that combining biomarkers — one for Alzheimer's disease and one for dementia with Lewy bodies — improves our ability to discriminate between disorders," presenter James Galvin, MD, from New York University in New York City, said at the meeting. More 4,223 whooping cough cases this year in California so far, highest in 55 years Medical News Today Share
The current 4,223 confirmed, probable and suspect cases of whooping cough (pertussis) reported in California up the September 21, 2010 is the highest since 1955, when there were 4,949 cases. With over three months to go till the end of the year, there is a good chance a new record will be broken. For this year so far, the state has a whooping cough rate of 10.79 cases per 100,000 people, says the California Department of Public Health. More
Fasting glucose and HbA1c may be useful to predict diabetes Medscape Medical News Share
Fasting glucose and glycated hemoglobin (HbA1c) levels may be useful to predict diabetes, according to the results of population-based analyses reported in Diabetes Care. "Although … HbA1c is now recommended to diagnose diabetes, its test performance for diagnosis and prognosis is uncertain," write Elizabeth Selvin, PhD, MPH, from the Johns Hopkins Bloomberg School of Public Health in Baltimore, and colleagues. "Our objective was to assess the test performance of HbA1c against single and repeat glucose measurements for diagnosis of prevalent diabetes and for prediction of incident diabetes." More More evidence links a virus to obesity, this time in children Los Angeles Times Share
New evidence indicates that children who are exposed to a virus called adenovirus-36 are more likely to be obese than those who are not exposed to it, and to be heavier than other obese kids who were not exposed to it, researchers said this week. The virus, known informally as Ad-36, is one of about 55 adenoviruses that are known to cause colds and is the only member of the family to be linked to obesity. But it is one of 10 bacteria and viruses that have been associated with a propensity for putting on plural poundage. More
New test for heart, kidney transplant rejection HealthDay News via Bloomberg Businessweek Share
A new blood test may offer a quicker, noninvasive way to detect organ rejection in heart and kidney transplant patients before the new organs are damaged, say researchers from the Stanford School of Medicine in California. They found that levels of three easily measured proteins rise in the blood during acute rejection, in which a transplant patient's immune system attacks the new organ. More FDA panel endorses new digital mammography technology Medscape Medical News Share
The Radiological Devices Advisory Panel has told the U.S. Food and Drug Administration that it is unequivocally in favor of granting Hologic Inc (Bedford, Mass.) a premarket approval application for its new breast imaging technology, the Selenia Dimensions 3-D system. The system captures 3-D images of the breast which, when properly read, can enhance the detection of tumors that may escape notice with currently available screening methods. It is also capable of acquiring conventional 2-D full-field digital mammography (2-D FFDM) images, and it is intended for use for the same clinical applications. More |
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